1 Answer - Posted in: gabapentin, dosage, blood disorders - Answer: Hi.. yes..High Blood Sugar rare side effects of Neurontin.. please consult Though gabapentin has many potential uses, it can cause side effects. Read more about 13 gabapentin side effects here. Gabapentin is not directly linked to causing high blood sugar, but it can influence weight gain, which may affect blood sugar levels. Understanding Gabapentin Gabapentin, originally developed as an anticonvulsant medication, is primarily used to treat epilepsy and neuropathic pain. It works by modulating the release of neurotransmitters in the brain, which can help alleviate pain and prevent Therefore, based on the case report and reported hyperglycemia in clinical trials, it seems gabapentin can cause mild blood glucose disturbances for an unknown mechanism of action. Gabapentin can help control seizures as well as nerve pain from shingles. It may sometimes cause side effects, especially if you misuse it. Learn more. People with diabetes may experience hypoglycemia due to the condition itself or its treatments. Even people who don’t have diabetes may experience hypoglycemia after taking certain medications. Her blood glucose level was 33 mg/dL. Gabapentin was started 1 week prior to the hypoglycemia episode. Her past medical history, concomitant medications, and other laboratory findings were not likely causes of her severe hypoglycemia. Conclusion: Gabapentin appears to have effects on several voltage-gated calcium channels. Recent research suggests that this may not occur. _________________ Because of the constantly changing nature of the U.S. prescription and OTC drug marketplace, this list may not reflect the full range of drugs that may impact blood glucose levels. The information contained in this document is intended as an educational aid only. It is not intended as medical advice for individual conditions Check whether Blood glucose abnormal is associated with a drug or a condition. On May, 10, 2025 313,421 people reported to have side effects when taking Gabapentin. Among them, 362 people (0.12%) have Blood glucose abnormal. Hyperglycemia is listed as a possible adverse drug reaction in the labeling. Case reports describe hypoglycemia in patients with diabetes, peritoneal dialysis, and/or incomplete medication records. The following case report details a hypoglycemia episode as a potential result of a gabapentin use in a patient without diabetes. Although blood glucose fluctuations are a possible adverse drug reaction (ADR) of gabapentin 1, hypoglycaemia in relation to this drug was found in just one publication 3. We received six cases of (severe) hypoglycaemia in both diabetic and non-diabetic patients exposed to gabapentin, which occurred between July 2002 and July 2012. The SmPC of gabapentin mentions blood glucose fluctuations in diabetic patients as a potential adverse drug reaction with unknown frequency [1]. The current observation describes the association between gabapentin and severe hypoglycaemia in diabetic and nondiabetic patients . Gabapentin is an anticonvulsant medication prescribed for a variety of conditions. Learn about its uses, side effects, and what you should know if you've been prescribed this medication. CONCLUSIONS: Hypoglycemia is a rarely acknowledged adverse effect of gabapentin overdose and requires urgent intervention as it could be initially resistant to simple glucose replacement and may lead to serious consequences. In this case, blood glucose levels responded only to high concentration dextrose infusion (D10) with concomitant tube feeds. Although blood glucose fluctuations are a possible adverse drug reaction (ADR) of gabapentin [1], hypoglycaemia in relation to this drug was found in just one publication [3]. We received six cases of (severe) hypoglycaemia in both diabetic and non-diabetic patients exposed to gabapentin, which occurred between July 2002 and July 2012. Began some medical journal research and found an obscure paper indicating that, in rare instances, gabapentin may cause lowering of blood sugar. Since then my oral blood sugar medication requirements have dropped significantly. 4. Gabapentin May Mask Symptoms of Worsening Conditions By dulling nerve pain without addressing its cause, gabapentin could potentially hide signs of a worsening condition. This is particularly concerning for diabetic patients, where neuropathy can be an early warning sign of poor blood sugar control or developing complications.
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