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Magnesium oxide (mineral supplement): Taking magnesium oxide with gabapentin may reduce the absorption of gabapentin. Cimetidine (histamine H2 receptor antagonist): Cimetidine may increase the concentration of gabapentin in the blood. Gabapentin is a common prescription medication. But if you’re taking it, you should be mindful of interactions with supplements or medications containing magnesium. Magnesium is a natural mineral, but it can still interact with other medications and supplements. Magnesium can lower the absorption of bisphosphonates, some antibiotics and antiviral medications, and gabapentin (Neurontin) if they’re taken together. In some cases, separating the two products can help you avoid the interaction. 230 medications are known to interact with magnesium oxide. Includes gabapentin, lisinopril, prednisone. Magnesium should not be taken with certain medications, including some antibiotics, diabetes drugs, diuretics, and others. Abstract The aim of this open-label, randomized, and 3-period crossover study was to evaluate the influences of concomitant antacid administration on the plasma disposition, intestinal absorption, and urinary excretion of gabapentin in humans. Gabapentin (200 mg) was orally administered alone, with 1 g magnesium oxide (MgO), or with 20 mg omeprazole to 13 healthy adult subjects. Oral A phase IV clinical study of FDA data: drug interactions are found among 12,076 people who take Magnesium (magnesium) and Gabapentin (gabapentin). A Minor Drug Interaction exists between gabapentin and magnesium oxide. View detailed information regarding this drug interaction. Can I take magnesium while taking gabapentin? Gabapentin and magnesium can interact with each other. Magnesium can lower the effects of gabapentin. If you've been prescribed gabapentin and take a medication or supplement containing magnesium, it's recommended to take gabapentin at least 2 hours after taking it. Magnesium oxide and Gabapentin drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Magnesium oxide (magnesium) and Gabapentin (gabapentin). Common drug interactions include vomiting among females and abdominal distension among males. Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Because gabapentin must be taken at bedtime, and magnesium helps with sleep, plus splitting the dose helps with side effects. I would be surprised if anyone at all with migraine wasn't taking them together. A Minor Drug Interaction exists between gabapentin and Mag-Oxide. View detailed information regarding this drug interaction. Review detailed drug interaction details between Gabapentin and Magnesium Oxide, including severity, interaction details, how to manage the interaction, and more. Learn about the potential interactions, benefits, and precautions of taking magnesium with gabapentin. Find out how to safely combine these two supplements for improved health. What drugs should you not take with gabapentin? Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Interaction Details Gabapentin is classified as belonging to the following category: Gabapentin (Neurontin) Gabapentin absorption can be decreased by magnesium. Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to
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