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Gabapentin is chemically similar to GABA (gamma-aminobutyric acid), a calming chemical in the brain. While it doesn't work exactly like GABA, it seems to reduce nerve pain by regulating how certain neurotransmitters are released in the central nervous system. This helps calm overactive nerve signals that make the body more sensitive to pain. The thing about Gabapentin is that it will work if u take enough. I am prescribed 600 mg 5x's a day. However I wish I never started. I've been on that dose now for 6.5 years. It doesn't do a thing for my anxiety anymore. Most doctors will prescribe gabapentin first; if that doesn't work, they will try pregabalin. You may experience side effects, such as drowsiness, dizziness, confusion, or swelling in the feet and legs. These side effects are limited by starting with a low dose and slowly increasing it. Why is my Neurontin (gabapentin) Not Working? Many times we have patients that have tried neurontin and reported it does not work. However, they dont realize the normal minimal dose needed to get a benefit is 1200 mg/day. On occasion patients try it and only go to 300 or 600 mg /day and then think it doesn’t work. If the side effects of the gabapentin are making it difficult for you to function and you can think more clearly without it. Then if you can manage the pain without gabapentin, I would get off of it. I would talk to your doctor to make sure he knows how you feel about the gabapentin and that it’s not helping you. I, initially was prescribed Gabapentin. It did NOT help, but I was urged to stick with it, because it might take time. I stuck with it for at least 3 years, without better results. My insurance would not approve Lyrica. After about 3 years, I developed mild hives. At that point, insurance approved Lyrica. Lyrica did not provide any improvement. Easy-to-read patient tips for gabapentin covering how it works, benefits, risks, and best practices. I husband has been on gabapentin for approximately two years. He feels that it’s not working as well anymore. Does gabapentin stopped working as well after taking a certain length of time? A safe, supportive environment for online support and information for those with neurological and related conditions. Gabapentin does not work for me. Gabapentin does not work for me, it just makes me tired, foggy, and confused. I have been on a number of pain medications and gabapentin doesn’t take away any of my pain at all. The reason why i was put on gabapentin is because my liver enzymes were to high with the other medication i was on. If gabapentin doesn’t work for my intercostal neuralgia pain, should I switch to another anticonvulsant or go down the anti depression route? I’ve felt zero relief from gabapentin, been on it for almost 3 weeks. 600mg throughout the day. I’m gonna wait longer to see if it kicks in soon and probably get another dosage increase. WebMD reports on what else you and your doctor might consider if your pain medication isn't working. In recent years gabapentin has stopped working for many people. Let's get into the reasons why this is happening. One of the most widely prescribed prescription drugs, gabapentin, is being taken by millions of patients despite little or no evidence that it can relieve their pain. In 2006, I wrote about 2 Answers - Posted in: pain, back pain, gabapentin, medication - Answer: Same for me. I gained weight in it also, that is the MAIN reason I nixed Gabapentin is approved for treating seizures and nerve pain, yet 95 percent of the time it’s used for other conditions, without strong research to back it up. With recent links to overdose and Gabapentin doesn't work for diabetic neuropathy. Here's the real reason neurontin fails diabetic neuropathy sufferers every single time. I haven’t heard of neurontin making neuropathy worse but maybe it is not the correct medication for you? Other meds used are Pregablin (Lyrica) which is an epileptic like neurontin and also an antidepressant called Cymbalta. I take a combo of Amitriptyline (an older antidepressant used for nerve pain) and Neurontin. Conclusion – What Next If Gabapentin Does Not Work? Finding alternatives becomes essential when gabapentin fails to deliver adequate relief from symptoms associated with nerve-related issues or other chronic conditions. Is your trigeminal neuralgia medication not working? Learn more about other treatments and surgeries that may help.
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