Regular gabapentin use appeared to increase risk of dementia by 29% and mild cognitive impairment (MCI) by 85%, researchers reported July 10 in the journal Regional Anesthesia & Pain Medicine. What’s more, the risk was more than doubled in people normally considered too young to suffer from brain aging, those 18 to 64, results show. Frequent use of gabapentin for back pain may raise the risk of dementia by 29% and mild cognitive impairment by 85%, new study finds. Long-term Gabapentin therapy for chronic pain is not associated with a differential risk of dementia across dosage levels, irrespective of age or gender. Further study into its potential cognitive impacts is essential. New data suggest an association between gabapentin for chronic back pain and increased risk of cognitive impairment, although experts urge caution in drawing any firm conclusions. The first patient with Alzheimer's Dementia was followed for months while the second patient with mixed dementia patient was only followed for three weeks. Next, it is unclear whether gabapentin is equally efficacious in Alzheimer's dementia versus concomitant Alzheimer's and vascular dementia. Conclusions Gabapentin prescription in adults with chronic low back pain is associated with increased risk of dementia and cognitive impairment, particularly in non-elderly adults. Physicians should monitor cognitive outcomes in patients prescribed gabapentin. Objective: Previous studies have shown that gabapentin or pregabalin use is associated with cognitive decline. Herein, we aimed to evaluate the association between gabapentin or pregabalin use and the risk of dementia. Methods: In this Introduction Dementia with Lewy Bodies (DLB) [1] is a common and dev-astating geriatric illness with challenging behavioral symptoms. Anipsychotics are poorly tolerated [2] and alternative pharma-cological approaches need to be explored. GBP, an anticonvul-sant and analgesic [3] is generally safe and well tolerated. GBP has been used for treatment of patients with various demen-tias and in Common Pain Drug Gabapentin Linked To Dementia Diagnoses In Adults Research shows that patients with six or more prescriptions for gabapentin, commonly used to treat lower back pain, were 29% more likely to be diagnosed with dementia and 85% more likely to be diagnosed with mild cognitive impairment within 10 years of their initial pain diagnosis. The association of gabapentin use and change of cognitive and functional status in older adults with normal cognition GYeon Oh, University of Kentucky / Sanders-Brown Center on Aging, Lexington, KY, USA. The adverse events from gabapentin could be higher in older adults who have more polypharmacy, higher comorbidities, and decreased renal functions. Since gabapentin is also prescribed to treat behavioral and psychological symptoms of dementia (BPSD) 19, gabapentin could be widely prescribed in patients with dementia. As we mentioned above, in most of the reviewed cases gabapentin is reported to be a well-tolerated and effective treatment for dementia-associated agitation. However, several case reports in which gabapentin was used for agitation in dementia with Lewy bodies question its appropriateness for all types of dementia-related agitation [14 – 16]. To explore the association between gabapentin use and the risk of dementia in patients with chronic pain, considering the rising concerns of dementia Introduction Gabapentin, an anticonvulsant medication, has gained popularity in recent years for treating various conditions in elderly patients, including neuropathic pain, epilepsy, and behavioral symptoms associated with dementia. However, as with any medication, its use in older adults comes with unique considerations. This article delves into the safety profile of gabapentin for elderly Gabapentin prescription in adults with chronic low back pain is associated with increased risk of dementia and cognitive impairment, particularly in non-elderly adults. Physicians should monitor cognitive outcomes in patients prescribed gabapentin. Gabapentin, often prescribed for chronic back pain, may raise the risk of dementia and memory issues, according to a study of over 50,000 adults. The effect was strongest in people aged 35–64 with frequent prescriptions. Background Gabapentin has been increasingly prescribed to older adults for off-label indications, and accumulating evidence suggests potential for gabapentin misuse and related adverse events. Howev Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and In most of the reviewed cases, gabapentin was reported to be a well tolerated and effective treatment for BPSD. However, two case reports in which gabapentin was used in the context of agitation in dementia with Lewy bodies questioned the appropriateness of gabapentin for all types of dementia-related agitation. Frequent use of common pain drug linked to increase in dementia and cognitive decline, study suggests.
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