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Painful Gynecomastia: An Unusual Toxicity of Gabapentin? To the Editor: Gabapentin is a new anticonvulsive drug fre-quently used for the treatment of various neu-ropathic pain conditions. 1–3 It is also increas-ingly used in palliative care. 4 Toxicity of this drug, although mild in most non-cancer pa-tients, may differ in patients with cachexia and exhaustion due to cancer. Long-term I’m on Abilify and Gabapentin, T rarely interferes with any drugs because it’s just a synthetic version of the testosterone everyone has in their system. You definitely don’t have to quit your meds for it. I was prescribed gabapentin several years ago as an adjunct anti-epileptic and I too feel little, if any, effects from it. Many others report experiencing it the same way. For Males here who being using Gabapentin for long time, Can Gabapentin really cause permanently erectile dysfunction ? We would like to show you a description here but the site won’t allow us. I (48F) have been on lo-dose birth control and topical testosterone for about 2 years. Been in Peri for 3-4 years. This treatment has helped tremendously on most of my peri symptoms except night sweats and horrible sleep. My Dr. is recommending non-hormonal options to treat this. She gave me 2 options, 1) gabapentin at 100-300 mg or 2) SNRIs (effexor or cymbalta at 37.5 mg). Both options have This report addresses dose-dependent gabapentin-induced sexual dysfunction reaching total sexual dysfunction (loss of libido, anejaculation, anorgasmia, and impotence) at a total daily dose of only 300 mg. I'm gonna consult with a doctor to see if Gabapentin is for me, but I had to ask here first - have you guys notified any significant hormonal changes since starting daily use? Hello - the providers at our institution were recently asked not to send controlled substances across state lines given the “DEA limits such activity”. I want to be able to reference something if I get pushback from patients — can anyone point me to a central resource reviewing controlled substance legislation/rules ? Is it state specific? I am in Michigan for reference. This comprehensive analysis explores the impact of gabapentin on testosterone levels, providing valuable insights and information for individuals concerned about potential hormonal effects of the medication. I began taking Gabapentin around the time I turned 42. I don’t know if my testosterone dipped because of my age or from the medication. My blood test showed 384 ng/dl. I have no sex drive, no motivation, weak erections, way less semen, and I can’t lose weight. This subreddit is for questions and discussion related to testosterone replacement therapy and testosterone. It also focuses on lifestyle activities like exercise and nutrition for raising testosterone levels naturally or anything else related to testosterone the substance. At least be sure they don't use the medication anymore. Past a certain point, gabapentin bioavailability begins to reduce. This means that taking more means it will actually be weaker (source) I lol whenever I read a comment about somebody taking 40 or so pills and complaining about how everybody else is bullshitting about the gabapentin high. Gabapentin may inhibit enzymatic processes necessary for testosterone production - it reduces levels of certain proteins and enzymes needed for steroidogenesis. It may bind to and influence hormonal receptors involved in regulating testosterone. Drug interactions are reported among people who take Gabapentin (gabapentin) and Testosterone (testosterone). Common drug interactions include asthma among females and fall among males. Impact on Testosterone For men, the study found that opioids such as hydrocodone, oxycodone, and morphine reduced free testosterone, while opioids methadone, fentanyl, and tramadol, and non-opioids gabapentin and pregabalin, had no effect. Testosterone is just a hormone, it signalizes to upregulate semen production but you don't literally lose it that way lol Yeah gabapentin I quit many many times over those 10 years they pretty much started me on the gabapentin and oxycodone at the same time. In my personal opinion the gabapentin was more addicting than the oxycodone. The only thing that seems to help me is Gabapentin (and Phenibut). I know the regular intake of Gabapentin will result in dependency and addiction. So to those who take Gabapentin long-.term, do you regret your decision to have started it? Do you still benefit from it? What are the major drawbacks? Please share your experience. For those who have tried gabapentin and/or estrogen/testosterone mix topical ointments for vulvodynia, how long did it take to notice improvements?
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