To obtain pilot prospective data regarding the efficacy and tolerability of gabapentin for alleviating hot flashes. The non-hormonal medicines used to reduce hot flushes in women include gabapentin, clonidine, venlafaxine or selective serotonin reuptake inhibitors (SSRIs). The treatment option depends on the individual. Gabapentin Brand name: Neurontin® available as 100mg, 300mg, 400mg, 600mg and 800mg capsules. Also available in generic brands. Venlafaxine was associated with increased nausea, appetite loss, constipation, and reduced negative mood changes compared with gabapentin, whereas gabapentin was associated with increased dizziness and appetite compared with venlafaxine (all P < .05). Conclusion: Breast cancer survivors prefer venlafaxine over gabapentin for treating hot flashes. Venlafaxine is used to treat major depressive disorder, anxiety, and panic disorder. Learn about side effects, interactions and indications. This study included seven trials of newer antidepressants and three trials of gabapentin. The optimal doses (defined by individual study results) of the newer antidepressants paroxetine, venlafaxine, fluoxetine, and sertraline decreased hot flash scores by 41%, 33%, 13%, and 3% to 18% compared with the corresponding placebo arms, respectively. Venlafaxine is used primarily for the treatment of depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. [15] Venlafaxine has been used off label for the treatment of diabetic neuropathy [16] and migraine prevention. [17] It may work on pain via effects on the opioid receptor. [18] It has also been found to reduce the severity of 'hot flashes' in Venlafaxine tablets are prescribed for depression and social anxiety disorder. Learn about dosage, side effects, how it compares with Xanax, and more. Learn about venlafaxine usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Compare Gabapentin vs Venlafaxine head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Hot flash reduction did not differ by tamoxifen or aromatase inhibitor use. Citalopram 10, 20, and 30 mg daily had comparable outcomes. Venlafaxine 75 mg daily improved hot flashes without additional side effects from higher dosing. Gabapentin 900 mg daily improved hot flashes more than 300 mg. Paroxetine 10 mg daily had fewer side effects than 2010 – Gabapentin vs venlafaxine (n=66 overall; crossover study) – was a cross-over trial with 2-4 weeks in between study periods. The authors reported that with regard to hot flash frequency, the ratio of venlafaxine compared to gabapentin was 0 Bordeleau 2010 – Gabapentin vs venlafaxine (n=66 overall; crossover study) – was a cross-over trial with 2-4 weeks in between study periods. The authors reported that with regard to hot flash frequency, the ratio of venlafaxine compared to gabapentin was 0.94 (95% CI not reported, but the p-value was reported to be >0.61). The authors also reported that 38 of 56 patients completing the Selective serotonin reuptake inhibitors (SSRIs [fluoxetine, sertraline, paroxetine]) and the selective norepinephrine reuptake inhibitor (SNRI) venlafaxine, as well as clonidine and gabapentin, reduce hot flashes by about 25% (approximately one per day) in women with and without a history of breast cancer. No studies compare medications against each other to determine a single best option What is the best nonhormonal therapy to treat hot flashes? Learn more about the new menopause treatment guidelines from a Mayo Clinic expert. Detailed Venlafaxine dosage information for adults. Includes dosages for Depression, Panic Disorder, Generalized Anxiety Disorder and more; plus renal, liver and dialysis adjustments. Description Venlafaxine is used to treat depression. It is also used to treat general anxiety disorder, social anxiety disorder, and panic disorder. Venlafaxine belongs to a group of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRI). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain. This medicine is available Venlafaxine is an antidepressant that may also be used for mood disorders and off-label for some other conditions such as hot flashes. It may cause a discontinuation syndrome if abruptly stopped after long-term administration. Find patient medical information for Venlafaxine (Effexor) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Venlafaxine is also sometimes used to treat hot flashes (hot flushes; sudden strong feelings of heat and sweating) in women who have experienced menopause ('change of life'; the end of monthly menstrual periods) or who are taking medication to treat breast cancer. Talk to your doctor or pharmacist about the risks of using venlafaxine to treat your condition. This medication is sometimes Forty-five percent of patients receiving low-dosage venlafaxine (37.5 mg daily) experienced at least a 50 percent reduction in hot flashes, compared with 63 percent of patients receiving a
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