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Although blood glucose fluctuations are a possible adverse drug reaction (ADR) of gabapentin 1, hypoglycaemia in relation to this drug was found in just one publication 3. We received six cases of (severe) hypoglycaemia in both diabetic and non-diabetic patients exposed to gabapentin, which occurred between July 2002 and July 2012. The SmPC of gabapentin mentions blood glucose fluctuations in diabetic patients as a potential adverse drug reaction with unknown frequency [1]. The current observation describes the association between gabapentin and severe hypoglycaemia in diabetic and nondiabetic patients . The Importance of Monitoring Blood Sugar Levels When starting any new medication like Gabapentin, monitoring blood sugar levels becomes even more critical. Changes in appetite or activity levels due to side effects could lead to fluctuations in blood glucose levels. Regular monitoring helps ensure that any necessary adjustments can be made Conclusion: A 63-year-old Caucasian gentleman with type 2 diabetes mellitus developed a possible case of gabapentin-induced mild hyperglycemia after receiving gabapentin for several months with a dose titration. Gabapentin could be considered as a cause for otherwise unexplained hyperglycemia in a patient. Do you take Gabapentin and are concerned about Hyperglycemia? eHealthMe's data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Check whether Hyperglycemia is associated with a drug or a condition. Postmarketing research of gabapentin has shown fluctuation of blood glucose levels. Ask your doctor to evaluate your blood glucose levels for hypoglycemia. He/she might want to adjust your dose of gabapentin, or send you to a dietician to establish a special diet to control the low blood sugar if your glucose is not dropping too severely. K From statins and antidepressants to antibiotics, here’s a list of drugs that may raise your blood sugar — and what you can do about it. Hyperglycemia is listed as a possible adverse drug reaction in the labeling. Case reports describe hypoglycemia in patients with diabetes, peritoneal dialysis, and/or incomplete medication records. The following case report details a hypoglycemia episode as a potential result of a gabapentin use in a patient without diabetes. Hi.. yes..High Blood Sugar rare side effects of Neurontin.. please consult with your health care provider as soon as possible.. good luck. Learn about the link between Gabapentin and elevated blood sugar, including potential side effects and precautions to take when using this medication. Conclusion: A 63-year-old Caucasian gentleman with type 2 diabetes mellitus developed a possible case of gabapentin-induced mild hyperglycemia after receiving gabapentin for several months with a dose titration. Gabapentin could be considered as a cause for otherwise unexplained hyperglycemia in a patient. CONCLUSIONS: Hypoglycemia is a rarely acknowledged adverse effect of gabapentin overdose and requires urgent intervention as it could be initially resistant to simple glucose replacement and may lead to serious consequences. In this case, blood glucose levels responded only to high concentration dextrose infusion (D10) with concomitant tube feeds. Gabapentin is an anticonvulsant medication prescribed for a variety of conditions. Learn about its uses, side effects, and what you should know if you've been prescribed this medication. Gabapentin is not directly linked to causing high blood sugar, but it can influence weight gain, which may affect blood sugar levels. Understanding Gabapentin Gabapentin, originally developed as an anticonvulsant medication, is primarily used to treat epilepsy and neuropathic pain. It works by modulating the release of neurotransmitters in the brain, which can help alleviate pain and prevent Food and exercise aren’t the only things that can raise your blood sugar. Learn about the effect of non-diabetes medicines. She received 4200 mg of gabapentin weekly for neuropathic pain, where 900 mg weekly was recommended for patients undergoing haemodialysis. Nadir blood glucose was 1.9 mmol l−1 which was corrected with dextrose. The patient recovered 3 days after with-drawal of gabapentin. Hypoglycemia may be due to gabapentin binding to the alpha 2 delta subunit of the calcium channels in the pancreas. Future research should investigate gabapentin and the potential for hypoglycemia. Keywords: blood glucose; gabapentin; hypoglycemia; patient case report.
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