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The essential guide to gabapentin for vulvodynia - discover all the essential information about one of the most popular medical vulvodynia treatment options, including usage, dosage, best practices, side effects, interactions, contraindications, and warnings. Vulvodynia is a leading cause of dyspareunia in premenopausal women, causing considerable morbidity and sexual dysfunction. A multimodal approach is used to treat vulvodynia. Alongside psychosocial interventions and physiotherapy, pharmacological treatment such as oral gabapentin are used in the treatment of vulvodynia. To evaluate whether extended-release gabapentin is more effective than placebo among women with vulvodynia. In a multicenter double-blind, placebo-controlled randomized crossover trial, gabapentin (1200 – 3000 mg/day) was compared to placebo. The View This Abstract Online Topical gabapentin in the treatment of localized and generalized vulvodynia. Obstet Gynecol. 2008; 112 (3):579-85 (ISSN: 0029-7844) Boardman LA; Cooper AS; Blais LR; Raker CA OBJECTIVE: To evaluate the clinical efficacy and tolerability of topical gabapentin in the treatment of women with vulvodynia. METHODS: A retrospective study was designed to ascertain clinical Topical Gabapentin in the Treatment of Localized and Generalized Vulvodynia From the 1 Department of Obstetrics and Gynecology, Women and Infants' Hospital of Rhode Island, the Warren Alpert Medical School of Brown University, Providence; and 2 Pawtuxet Valley Prescription and Surgical Center, Inc., Coventry, Rhode Island. Objective Vulvodynia is a leading cause of dyspareunia in premenopausal women, causing considerable morbidity and sexual dysfunction. A multimodal approach is used to treat vulvodynia. Alongside psychosocial interventions and physiotherapy, pharmacological treatment such as oral gabapentin are used in the tre A retrospective study was designed to ascertain clinical responses to topical gabapentin. Patient demographic and medical characteristics, including present and prior treatment for vulvodynia, were routinely collected. The final outcome was defined by a comparison between pretreatment and Vulvodynia is a poorly understood yet common and highly uncomfortable chronic condition with no satisfactory treatment. Extrapolating from the usefulness of oral gabapentin for vulvodynia, investigators conducted a retrospective case series review of 51 patients who had been treated with topical gabapentin for generalized or localized vulvodynia. Between January 2001 and December 2006, 51 women with vulvodynia (19 or 37% with generalized vulvodynia, 32 or 63% with localized) were treated with 2% to 6% gabapentin. Of the 210 women diagnosed with generalized or localized vulvodynia, 51 (24%) received topical gabapentin, either alone or combined with other medication(s). Many participants had tried other treatments prior to commencing gabapentin treatment (topical lidocaine (19 of 51; 37%), antifungals (17 of 51; 33%), hormonal medications (16 of 51; 31% Treatment of hyperpathic itching The complexity of pruritus often requires a combination of systemic and topical therapies, using those medications that are used for vulvodynia. The topic is not well studied. (treatments above). Twenty-five trials explored the use of oral and topical medications in the treatment of vulvodynia. Data Synthesis: Vulvodynia is a poorly understood disease with an unknown etiology. Oral tricyclic antidepressants and gabapentin continue to be the most commonly used treatments for vulvodynia pain. Abstract Vulvodynia is a leading cause of dyspareunia in premenopausal women, causing considerable morbidity and sexual dysfunction. A multimodal approach is used to treat vulvodynia. Alongside psychosocial interventions and physiotherapy, pharmacological treatment such as oral gabapentin are used in the treatment of vulvodynia. Topical formulations of gabapentin have shown promise in animal Results: Between January 2001 and December 2006, 51 women with vulvodynia (19 or 37% with generalized vulvodynia, 32 or 63% with localized) were treated with 2% to 6% gabapentin. After a minimum of 8 weeks of therapy, the mean pain score among the 35 evaluable women was significantly reduced from 7.26 to 2.49 (mean change -4.77, 95% confidence interval -5.47 to -4.07). Overall, 28 of 35 (80% Vulvodynia is a debilitating condition characterized by chronic vulvar pain, with a detrimental impact on the patient's overall quality of life. Its etiology is multifactorial, but still in the process of being clearly outlined. Between January 2001 and December 2006, 51 women with vulvodynia (19 or 37% with generalized vulvodynia, 32 or 63% with localized) were treated with 2% to 6% gabapentin. Topical pharmacologic treatment for vulvodynia falls into 4 categories: local anesthetics, anti-inflammatories, antidepressants, and other drugs. Each of these aims to target pain modulation or pathologies implicated in vulvodynia such as inflammation, muscle spasm, or hormone imbalance. Among the 20 evaluable women with localized vulvodynia, they also found that 17 reported improved sexual function. Boardman LA, Cooper AS, Blais LR, et al. Topical gabapentin in the treatment of localized and generalized vulvodynia. Obstet Gynecol. 2008;112:579-585. Recent Videos A multimodal approach is used to treat vulvodynia. Alongside psychosocial interventions and physiotherapy, pharmacological treatment such as oral gabapentin are used in the treatment of vulvodynia. Abstract To evaluate the clinical efficacy and tolerability of topical gabapentin in the treatment of women with vulvodynia. A retrospective study was designed to ascertain clinical responses to topical gabapentin. Patient demographic and medical characteristics, including present and prior treatment for vulvodynia, were routinely collected.
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