Gabapentin Pregnancy and Breastfeeding Warnings Brand names: Fanatrex, Gabarone, Gralise, Neurontin Medically reviewed by Drugs.com. Last updated on Jun 24, 2025. Pregnancy Warnings Breastfeeding Warnings Gabapentin Pregnancy Warnings Benefits should clearly outweigh risks AU TGA pregnancy category: B3 US FDA pregnancy category: Not assigned Risk Summary: There are no data on the developmental This sheet discusses gabapentin use during pregnancy and breastfeeding, offering guidance on potential risks and safety considerations. Gabapentin Maternal doses of gabapentin up to 2.1 g/day produce relatively low levels in infant serum. A single oral dose of either 300 or 600 mg given to the mother before cesarean section appeared to have no effect on breastfeeding initiation. Gabapentin is a γ-aminobutyric acid analog formally indicated for the treatment of epilepsy and neuropathic pain that is gaining increased popularity. Gabapentin has been historically considered a safe medication, including during pregnancy and lactation, with low reported concerns for misuse and us Gabapentin and breastfeeding: understand the potential risks and benefits. Learn about safety guidelines, possible side effects, and what to discuss with your doctor. DrLact safety Score for Gabapentin is 1 out of 8 which is considered Safe as per our analyses. A safety Score of 1 indicates that usage of Gabapentin is mostly safe during lactation for breastfed baby. Our study of different scientific research also indicates that Gabapentin does not cause any serious side effects in breastfeeding mothers. Most of scientific studies and research papers Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. Gabapentin is a Pregnancy Category C drug and Animal studies suggest that it can harm an unborn child and therefore should be avoided during pregnancy. This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. 3. Guidelines for Breastfeeding Mothers on Gabapentin Discuss with Your Healthcare Provider: Always consult with a healthcare professional before starting or continuing gabapentin while breastfeeding. They will weigh the potential benefits to the mother against the risks to the infant. gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring (1) published evidence for the use of gabapentin during breastfeeding is very limited. The aim of this study was to describe the milk-plasma ratio and relative infant dose of gabapentin in a breastfeeding mother and to determine the well-being of her exposed infant. The mother-infant pair was studied over a 24-hour dose interval at steady state. Gabapentin concentrations were quantifi If gabapentin or pregabalin is used by a breastfeeding mother, monitor the infant for gastrointestinal adverse effects, appetite changes, adequate weight gain, drowsiness and normal developmental milestones. This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. What is gabapentin? Gabapentin is a medication that has been used to prevent and control partial seizures, treat some forms [] NHS medicines information on gabapentin and whether you can take it while pregnant or breastfeeding. Data Sources: A search of MEDLINE (1966–1998) and the Lithium Database, Madison Institute of Medicine, was conducted to obtain articles about lithium, valproate, carbamazepine, gabapentin, or lamotrigine use during lactation. Search terms used were pregnancy, teratogenesis, breastfeeding, lactation, breast milk levels and lithium, anticonvulsants, mood stabilizers. No other search Advice for mothers using Gabapentin while breastfeeding. Includes possible effects on breastfed infants and lactation. Therefore, gabapentin, lamotrigine, oxcarbazepine, vigabatrin, tiagabine, pregabalin, leviracetam and topiramate are compatible with breastfeeding with a less documented safety profile. Ethosuximide, zonisamide and the continue use of clonazepam and diazepam are contraindicated during breastfeeding. Conclusions Limited information indicates that maternal doses of gabapentin up to 2.1 grams daily produce relatively low levels in infant serum. Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsant or psychotropic drugs. A single oral dose of either 300 mg or 600 mg given to Gabapentin or pregabalin can be taken during breastfeeding and with infant monitoring. Recommendations apply to full term and healthy infants only.
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