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Gabapentin is a γ-aminobutyric acid analog formally indicated for the treatment of epilepsy and neuropathic pain that is gaining increased popularity. Gabapentin has been historically considered a safe medication, including during pregnancy and lactation, with low reported concerns for misuse and use disorders. Buy Abstract Gabapentin is a γ-aminobutyric acid analog formally indicated for the treatment of epilepsy and neuropathic pain that is gaining increased popularity. Gabapentin has been historically considered a safe medication, including during pregnancy and lactation, with low reported concerns for misuse and use disorders. Ohman I, Tomson T. Gabapentin kinetics during delivery, in the neonatal period, and during lactation. Epilepsia 2009;50 (Suppl. 10):108. Abstract. Patorno E, et al. 2020. Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. DrLact safety Score for Gabapentin is 1 out of 8 which is considered Safe as per our analyses. A safety Score of 1 indicates that usage of Gabapentin is mostly safe during lactation for breastfed baby. Our study of different scientific research also indicates that Gabapentin does not cause any serious side effects in breastfeeding mothers. Most of scientific studies and research papers The aim of this study was to describe the milk-plasma ratio and relative infant dose of gabapentin in a breastfeeding mother and to determine the well-being of her exposed infant. The mother-infant pair was studied over a 24-hour dose interval at steady state. Gabapentin concentrations were quantifi The manufacturers of gabapentin recommend it should be used with caution in breastfeeding and only used where the benefits clearly outweigh the risks. (3) The manufacturers of pregabalin do not recommend use of pregabalin whilst breastfeeding. (4) This raises the question of the true compatibility of gabapentin and pregabalin whilst breastfeeding. Gabapentin and breastfeeding: understand the potential risks and benefits. Learn about safety guidelines, possible side effects, and what to discuss with your doctor. Gabapentinand breastfeeding gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring (1) published evidence for the use of gabapentin during breastfeeding is very limited. Data is from 10 mothers using gabapentin doses up to 2.1g daily limited information indicates that maternal doses of gabapentin up to 2.1 grams daily produce relatively NHS medicines information on gabapentin and whether you can take it while pregnant or breastfeeding. Advice for mothers using Gabapentin while breastfeeding. Includes possible effects on breastfed infants and lactation. Another prospective study in Norway followed infants of mothers who took antiepileptic drugs during pregnancy and lactation. These infants were compared with control groups of infants of mothers with untreated epilepsy and infants with fathers who took antiepileptics. 3 Infants were assessed at 6, 18, and 36 months of age. Although some impairment in fine motor skills was found in infants This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. What is gabapentin? Gabapentin is a medication that has been used to prevent and control partial seizures, treat some forms [] Summary of Use during Lactation Limited information indicates that maternal doses of gabapentin up to 2.1 grams daily produce relatively low levels in infant serum. Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsant or psychotropic drugs. A single oral dose of Therefore, gabapentin, lamotrigine, oxcarbazepine, vigabatrin, tiagabine, pregabalin, leviracetam and topiramate are compatible with breastfeeding with a less documented safety profile. Ethosuximide, zonisamide and the continue use of clonazepam and diazepam are contraindicated during breastfeeding. Conclusions Summary of Use during Lactation Limited information indicates that maternal doses of gabapentin up to 2.1 grams daily produce relatively low levels in infant serum. Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsant or psychotropic drugs. A single oral dose of Understanding Gabapentin Use During Breastfeeding Gabapentin, a medication commonly prescribed for nerve pain and seizures, raises important questions regarding its safety for breastfeeding mothers and their infants. As more women are prescribed this drug, understanding its implications during lactation becomes crucial. Safety Profile of Gabapentin in Breastfeeding Current research indicates Gabapentin or pregabalin can be taken during breastfeeding and with infant monitoring. Recommendations apply to full term and healthy infants only. Gabapentin is a Pregnancy Category C drug and Animal studies suggest that it can harm an unborn child and therefore should be avoided during pregnancy. Gabapentin Pregnancy and Breastfeeding Warnings Brand names: Fanatrex, Gabarone, Gralise, Neurontin Medically reviewed by Drugs.com. Last updated on Jun 24, 2025. Pregnancy Warnings Breastfeeding Warnings Gabapentin Pregnancy Warnings Benefits should clearly outweigh risks AU TGA pregnancy category: B3 US FDA pregnancy category: Not assigned Risk Summary: There are no data on the developmental
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