Gabapentin is a drug used to treat epilepsy and neuropathic pain, but its effects on pregnancy and breastfeeding are not well studied. Learn about the potential risks, benefits, and alternatives of using gabapentin during pregnancy and breastfeeding. Methods A systematic review was performed in PubMed and Reprotox using the search terms: “gabapentin”, “pregabalin”, “antiepileptic drugs” and terms associated with pregnancy. We included all studies in English that reported on the use and safety of gabapentin and pregabalin during pregnancy. This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. What is gabapentin? Gabapentin is a medication that has been used to prevent and control partial seizures, treat some forms [] This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. Is gabapentin safe during pregnancy? Learn about the potential risks and benefits of taking gabapentin while pregnant, and what you should discuss with your doctor. Gabapentin is a pregnancy category C drug that may increase the risk of embryo fetal toxicity and preterm birth. Learn about the animal studies, human research, and alternatives for gabapentin use during pregnancy. Overview of the five pregnancy risk categories, established by the FDA to indicate the potential of a drug to cause birth defects if used during pregnancy. Learn about the pregnancy category for Gabapentin and its possible effects on pregnancy and breastfeeding. Gabapentin is a γ-aminobutyric acid analog formally indicated for the treatment of epilepsy and neuropathic pain that is gaining increased popularity. Gabapentin has been historically considered a safe medication, including during pregnancy and lactation, with low reported concerns for misuse and use disorders. Gabapentin (Neurontin) is a Pregnancy Category C medication that can cause fetal malformation, urinary tract and kidneys problems, and miscarriages. Breastfeeding women should consult their healthcare provider before taking gabapentin as it is excreted into the breast milk and its safety is unknown. NEURONTIN is a drug used for postherpetic neuralgia and epilepsy. Based on animal data, it may cause fetal harm and is classified as Pregnancy Category C. Pregnancy Category C: Gabapentin has been shown to be fetotoxic in rodents, causing delayed ossification of several bones in the skull, vertebrae, forelimbs, and hindlimbs. This sheet discusses gabapentin use during pregnancy and breastfeeding, offering guidance on potential risks and safety considerations. Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. The objective of this study was to assess the safety of gabapentin (Neurontin) exposure in human pregnancy. Prospective and retrospective data concerning 51 fetuses, including 3 twin gestations, were collected from 39 women with epilepsy and other disorders exposed to gabapentin during pregnancy. Data were collected and evaluated about the 44 live births, including maternal demographics Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. Gabapentin is an anti-seizure drug and some of these can affect folic acid levels. Women taking gabapentin while trying to conceive and during pregnancy should therefore be prescribed a high dose folic acid supplement (5mg/day). Gabapentin is an antiepileptic drug used for various conditions, but its safety in pregnancy is unclear. A large study found no evidence of major malformations, but a slightly higher risk of preterm birth, small for gestational age, and NICU admissions. Despite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association between gabapentin exposure during pregnancy and risk of adverse neonatal and maternal outcomes. In this large population-based study, we did not find evidence for an association between gabapentin exposure during early pregnancy and major malformations overall, although there was some evidence of a higher risk of cardiac malformations. Maternal use of gabapentin, particularly late in pregnancy
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