Gabapentin may be prescribed either before or after surgery to help with postsurgical pain. However, it should be used with caution due to the high risk of abuse. y and safety of gabapentin for pain management following spinal surgery. Methods: In January 2017, a systematic computer-based search was conducted in PubMed, EMBASE, Web of Science, Cochrane Database of Systematic Reviews, and Google database. Data on patients prepared for spine surgery in studies that compared gabapentin versus placebo were retrieved. The primary endpoint was the visual Conclusion Gabapentin, pregabalin, and duloxetine have potential to further decrease post-operative pain and lower opioid dependency. This review creates an opening for further research in hand surgery to assess an updated protocol for pain management to reduce opioid dependency. The shift towards multimodal pain regimens, including gabapentin, has taken place without attention to ensuring that they, like opioids, are appropriately discontinued soon after surgery. The prevalence of prolonged use of post-operative gabapentin among older adults is unknown, as are the factors associated with prolonged use. Abstract Neuropathic pain after spinal surgery, the so-called failed back surgery syndrome (FBSS), is a frequently observed troublesome disease entity. Although medications may be effective to some degree, many patients continue experiencing intolerable pain and functional disability. Only gabapentin has been proven effective in patients with FBSS. No relevant studies regarding manipulation or It is a novel drug used for the treatment of postoperative pain with antihyperalgesic properties and a unique mechanism of action. Gabapentin and the related, more potent compound pregabalin have been shown to be beneficial in the treatment of neuropathic pain as well as postoperative pain following spinal surgery and hysterectomy. Previous studies investigating multimodal pain therapy in otolaryngology patients focused on homogenous patient groups with short postoperative follow-up times. Objective: To investigate the effect of perioperative gabapentin treatment on postsurgical pain in patients undergoing head and neck mucosal surgery. Factors Influencing Duration of Gabapentin Use Several factors come into play when determining how long gabapentin should be taken after surgery. First off, the type and extent of the surgical procedure significantly influence recovery time and pain levels. This systematic review and network meta-analysis evaluates the associations of pain, opioid consumption, and adverse events with different dosages of pregabalin and gabapentin in patients undergoing spine surgery. Would you want to take Lyrica (pregabalin) or Neurontin (gabapentin) for pain relief after a major surgery? Both drugs belong to a class of nerve medication called gabapentinoids that are increasingly being prescribed to patients perioperatively (after surgery) as an alternative to opioid medication. Abstract Perioperative pain management is a unique challenge in patients undergoing spine surgery due to the increased incidence of both pre-existing chronic pain conditions and chronic postsurgical pain. Peri-operative planning and counseling in spine surgery should involve an interdisciplinary approach that includes consideration of patient-level risk factors, as well as pharmacologic and The results from this study demonstrate that gabapentin is more beneficial in mastectomy and spinal, abdominal, and thyroid surgeries. Gabapentin is an effective analgesic adjunct, and clinicians should consider its use in multimodal treatment plans among patients undergoing elective surgery. This randomized clinical trial investigates the effect of perioperative gabapentin treatment vs placebo on postsurgical pain in patients undergoing head and neck mucosal surgery. Preoperative oral gabapentin decreased pain scores in the early postoperative period and postoperative morphine consumption in spinal surgery patients while decreasing some morphine-associated side effects. In 2006, Ho et al. performed a review of 16 randomized controlled trials (RCTs) evaluating the use of preoperative gabapentin in controlling postoperative pain (3). This was a very heterogeneous group that included orthopedic, gynecologic, urologic, breast, and head/neck surgeries. They showed that oral gabapentin was efficacious in the management of postoperative pain at every time point during the first day after surgery and therefore is efficacious in reducing postoperative pain and narcotic requirements after lumbar spinal surgery [49]. Conclusion Gabapentin, pregabalin, and duloxetine have potential to further decrease post-operative pain and lower opioid dependency. This review creates an opening for further research in hand surgery to assess an updated protocol for pain management to reduce opioid dependency. This review evaluated the efficacy and tolerability of peri-operative gabapentin administration to control acute post-operative pain. Peri-operative gabapentin administration was found to be effective in reducing pain scores, opioid requirements and opioid-related adverse effects in the first 24 hours after surgery. Given the significant differences between the studies and the possibility of Despite the use of new drugs and delivery modalities, studies have shown that acute postoperative pain continues to be undermanaged (1, 2). Approximately three of four patients experience acute pain after surgery, and 80% of these have moderate to extreme pain. Opioid analgesics are the cornerstone of pharmacological postoperative pain management (3), although they also contribute to increased
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