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Alas, a combination of antipsychotics, mood stabilizers and other classes of psychotropic medications is often the choice in this challenging patient population, despite the inconsistent and scant evidence for polypharmacy [11]. Gabapentin is a new adjunctive medication to antiseizure therapies. Anecdotal evidence suggests that it may also help to alleviate mood symptoms in patients with bipolar illness. An open-label study examined the effects of adjunctive gabapentin in bipolar patients with mixed symptoms who had previou This article reviews evidence-based psychiatric uses of gabapentin, along with associated risks. An extensive literature review was conducted, primarily of articles searchable in PubMed, relating to psychiatric uses, safety, and adverse effects of Gabapentin is currently being studied as a treatment for bipolar disorder, and there have been favorable reports regarding its potential as a mood stabilizer (82, 83). Gabapentin as an adjunct to standard mood stabilizers in out patients with mixed bipolar symptomatology. Ann Clin Psychiatry (1999) 11 (4):217–22. doi: 10.1023/a:1022361412956 Gabapentin (Trade name: Neurontin) is an anticonvulsant. It is commonly also used off-label for anxiety disorders, restless leg syndrome, and in alcohol use disorder. The relatively low frequency of bipolar disorder diagnoses in the sample of off-label gabapentin visits suggests that use of gabapentin as a mood stabilizer has declined, which corresponds with more recent psychopharmacology literature concluding that gabapentin’s mood-stabilizing effects are minimal to negligible (13, 32). A psychiatrist answers common questions about mood stabilizers for bipolar depression. Patients frequently express an interest in using gabapentin rather than standard mood-stabilizing agents (like lithium carbonate, divalproex sodium, or carbamazepine) due to its limited side effect profile. Thus, clinical interest regarding its use in mood disorders has grown. Explore gabapentin's role in mental health treatment, including its uses, benefits, and potential risks. Learn about dosage, effectiveness, and side effects. Gabapentin is a nerve pain medication and anticonvulsant that has proven to be effective for people who have hard-to-treat depression or other mood disorders. Gabapentin may be effective for treating depression and anxiety, among other things. Although gabapentin was traditionally used to treat seizures, it is now sometimes used as a mood stabilizer for depression and bipolar disorder because it calms neurons in the brain, and it may be effective for anxiety too. Key takeaways: Gabapentin is a medication that’s used to treat seizures, nerve pain from shingles, and restless leg syndrome. Despite previous marketing claims, there’s no evidence that gabapentin is a good treatment for bipolar disorder. The best treatment for bipolar disorder is therapy and a combination of other medications. These include mood stabilizers, anticonvulsants, and The gabapentinoids comprise gabapentin and pregabalin. Gabapentin is licensed for use in the USA for the treatment of focal seizures and post-herpetic neuralgia [1] and in the UK for focal Discover how gabapentin affects emotions, from potential benefits to side effects. Learn about managing mood changes and the importance of personalized care. Gabapentin is commonly used off-label in the treatment of psychiatric disorders with success, failure, and controversy. A systematic review of the literature was performed to elucidate the evidence for clinical benefit of gabapentin in psychiatric My psychiatrist recently put me on Gabapentin for as a mood stabilizer/ to address anxiety and depression ( we're exploring a possible Bipolar II diagnosis as well). Gabapentin is commonly used off-label in the treatment of psychiatric disorders with success, failure, and controversy. A systematic review of the literature was performed to elucidate the evidence for clinical benefit of gabapentin in psychiatric disorders. Off-label gabapentin (Neurontin) got a bad rep when it missed the mark in bipolar disorder, but there may be something worth salvaging in this drug. Here, we weigh its pros and cons for anxiety, substance use disorders, sleep, pain, and hot flashes, and compare it to its underutilized cousin, pregabalin (Lyrica).
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